Toxic Substances Control Act Chemical Testing; Receipt of Test Data

This Notice document was issued by the Environmental Protection Agency (EPA)

For related information, Open Docket Folder  Docket folder icon


ENVIRONMENTAL PROTECTION AGENCY
[EPA-HQ-OPPT-2005-0033; FRL-8872-4]

Toxic Substances Control Act Chemical Testing; Receipt of Test Data

Agency

Environmental Protection Agency (EPA).

Action

Notice.

Summary

This notice announces EPA's receipt of test data on 12 chemicals listed in the Toxic Substance Control Act (TSCA) section 4 test rule titled “Testing of Certain High Production Volume Chemicals.”

For Further Information Contact

For technical information contact: Kathy Calvo, Chemical Control Division (7405M), Office of Pollution Prevention and Toxics, Environmental Protection Agency, 1200 Pennsylvania Ave., NW., Washington, DC 20460-0001; telephone number: (202) 564-8089; fax number: (202) 564-4765; e-mail address: calvo.kathy@epa.gov.

For general information contact: The TSCA-Hotline, ABVI-Goodwill, 422 South Clinton Ave., Rochester, NY 14620; telephone number: (202) 554-1404; e-mail address: TSCA-Hotline@epa.gov.

Supplementary Information

I. General Information

A. Does this action apply to me?

This action is directed to the public in general. This action may, however, be of interest to those persons who are concerned about data on health and/or environmental effects and other characteristics of this chemical. Since other entities may also be interested, the Agency has not attempted to describe all the specific entities that may be affected by this action. If you have any questions regarding the applicability of this action to a particular entity, consult the person listed underFOR FURTHER INFORMATION CONTACT.

B. How can I get copies of this document and other related information?

All documents in the docket are listed in the docket index available at http://www.regulations.gov. Although listed in the index, some information is not publicly available, e.g., CBI or other information whose disclosure is restricted by statute. Certain other material, such as copyrighted material, will be publicly available only in hard copy. Publicly available docket materials are available electronically at http://www.regulations.gov, or, if only available in hard copy, at the OPPT Docket. The OPPT Docket is located in the EPA Docket Center (EPA/DC) at Rm. 3334, EPA West Bldg., 1301 Constitution Ave., NW., Washington, DC. The EPA/DC Public Reading Room hours of operation are 8:30 a.m. to 4:30 p.m., Monday through Friday, excluding legal holidays. The telephone number of the EPA/DC Public Reading Room is (202) 566-1744, and the telephone number for the OPPT Docket is (202)566-0280. Docket visitors are required to show photographic identification, pass through a metal detector, and sign the EPA visitor log. All visitor bags are processed through an X-ray machine and subject to search. Visitors will be provided an EPA/DC badge that must be visible at all times in the building and returned upon departure.

II. Test Data Submissions

EPA received test data on 12 chemicals listed in the TSCA section 4 test rule titled “Testing of Certain High Production Chemicals,” published in theFederal Registerissue of March 16, 2006 (71 FR 13708) (FRL-7335-2).

Section 4(d) of TSCA (15 U.S.C. 2603(d)) requires EPA to publish a notice in theFederal Registerreporting the receipt of test data submitted pursuant to test rules promulgated under TSCA section 4(a) (15 U.S.C. 2603(a)). Each notice must:

1. Identify the chemical substance or mixture for which data have been received.

2. List the uses or intended uses of such substance or mixture and the information required by the applicable standards for the development of test data.

3. Describe the nature of the test data developed.

The following table contains the information described in this document. See the applicable CFR cite, listed in this table, for test data requirements. EPA has completed its review and evaluation process for these submissions. Reviews have been added to the docket.

Table 1—Data Received in Response to a TSCA Section 4 Test Rule at 40 CFR 799.4115, Titled “Chemical Testing Requirements for Certain High Production Volume Chemicals,” Docket ID No. EPA-HQ-OPPT-2005-0033
Chemical identityData receivedDocument No. for the item in Docket ID No. EPA-HQ-OPPT-2005-0033Chemical use
Methane, dibromo (CASRN 74-95-3)Determination of Vapor Pressure0254, transmittal; 0254.1Organic synthesis, solvent.
Determination of General Physico-Chemical Properties0254 and 0254.2 
Algal Growth Inhibition Test0254 and 0254.3 
Chromosome Aberration Test in Human Lymphocytes In Vitro 0254 and 0254.5 
Acute Toxicity to Rainbow Trout0259, transmittal; 0259.1 
Acute Toxicity to Daphnia Magna0259 and 0259.2 
Oral (Gavage) Reproduction/Developmental Toxicity Screening Test in the Rat0259, 0259.3, part 1, and 0259.4, part 2 
1,3-Propanediol, 2,2-bis[(nitrooxy)methyl]-, dinitrate (CASRN 78-11-5)Reproductive and Developmental Effects of Oral Exposure to Pentaerythritol-Tetranitrate (PETN) in the Rat0294, transmittal; and 0294.1Demolition explosive, blasting caps, detonating compositions, “Primacord”.
1. Determination of the Water Solubility2. n-Octanol/Water Partition Coefficient3. Biodegradation Potential of Pentaerythritol Tetranitrate (PETN).0294 and 0294.2. Copyrighted document. See note 
Toxicity of Pentaerythritol Tetranitrate (PETN) to the Unicellular Green Alga (Selenastrum capricornutum) Under Static Test Conditions, Part 10294 and 0294.3 
Toxicity of Pentaerythritol Tetranitrate (PETN) to the Unicellular Green Alga (Selenastrum capricornutum) Under Static Test Conditions, Part 2, (PETN Analytical Report)0294 and 0294.4 
9,10-Anthracenedione (CASRN 84-65-1)Data for:1. Melting Point.2. Boiling Point.3. Vapor Pressure.0182, transmittal; 0211Intermediate for dyes and organics, organic inhibitor, and bird repellent for seeds.
Physical and Chemical Characteristics of Anthraquinone: n-Octanol/Water Partition Coefficient and Solubility0222, transmittal; 0222.1 
An Oral Reproduction/Developmental Toxicity Screening Study of Anthraquinone in Rats0222 and 0222.2 
2,4-Hexadienoic acid (2E, 4E) (Sorbic acid) (CASRN 110-44-1)Physical and Chemical Property Tests for:1. Melting Point.2. Water Solubility.3. n-Octanol/Water Partition Coefficient.4. Boiling Point.5. Vapor Pressure.0313 and 0335Fungicide, food preservative (mold inhibitor), alkyd resin coatings, upgrading of drying oils, cold rubber additive, and intermediate for plasticizers and lubricants.
Fathead Minnow 96-Hour Acute Toxicity Test  
Daphnia Magna 48-Hour Acute Toxicity Test  
Pimephales Promelas Acute Toxicity Test  
Dodecane, 1-chloro- (CASRN 112-52-7)Determination of the Boiling Point/Boiling Range of 1-Chlorodedecane0314, transmittal; 0314.6Solvent, chemical intermediate to make photographic chemicals, pharmaceuticals, organic metallic compounds, and surfactants.
Determination of the Vapor Pressure of 1-Chlorododecane Using the Static Method0314 and 0314.10 
1-Chlorododecane: Determination of n-Octanol/Water Partition Coefficient0314 and 0314.8 
Determination of the Water Solubility of 1-Chlorododecane0314 and 0314.11 
1-Chlorodecane: Evaluation of Ultimate Biodegradability in an Aqueous Medium-Static Test, ISO/FDIS 9888:1999(E)(1)) (Zahn-Wellens Method)0314 and 0314.9 
1-Chlorododecane: A 96-Hour Toxicity Test with the Freshwater Alga (Pseudokirchneriella subcapitata)0314 and 0314.5 
A Flow-Through Life-Cycle Toxicity Study of 1-Chlorododecane with the Cladoceran (Daphnia magna)0314 and 0314.7 
Acute Oral Toxicity with 1-Chlorododecane: Up and Down Procedure in Rats0314 and 0314.1 
A Combined 28-Day Repeated Dose Oral Toxicity Study with the Reproduction/Developmental Toxicity Screening Test of 1-Chlorododecane in Rats0314 and 0314.4 
Bacterial Reverse Mutation Assay of 1-Chlorododecane0314 and 314.2 
In Vitro Mammalian Chromosome Aberration Test0314 and 0314.3 
Phenol, 4,4′-methylenebis[2,6-bis(1,1-dimethyethyl)-(CASRN 118-82-1)Existing data for Determination of Water Solubility and n-Octanol/Water Partition Coefficient0163Oxidation inhibitor, anti wear agent for motor oils, aviation piston engine oils, industrial oils, anti oxidant for rubbers, resins, and adhesives.
Existing data for Bacterial Reverse Mutation Test (Ames Test)0181; transmittal; 0181.2 
Re submittal for Bacterial Reverse Mutation Test (Ames Test)0250, transmittal; 0250.1, and 0250.2 
Existing data for Acute Oral Mammalian Toxicity Test0181 and 0181.1 
Existing data for Reproduction/Developmental Toxicity Screening Test0181 and 0181.3 
Chromosomal Aberration Test with AN-2 Cultured Chinese Hamster Ovary (CHO) Cells0257. Copyrighted document. See note 
Activated Sludge Die-away Biodegradation Test with AN-2(4,4-methylenebis (2,6-di-tert-butylphenol) Using Non-adapted and Adapted Activated Sludge0275.1. Copyrighted document. See note 
1. Melting Point2. Boiling Point.3. Vapor Pressure.0274 
Methanesulfinic acid, 1-hydroxy-, sodium salt (1:1) (CASRN 149-44-0)1. Existing study for Biodegration Test according to OECD 301B: Degradation of a Product2. Existing study for Acute Toxicity to Fish According to DIN Method 384123. Existing study for Acute Toxicity to Daphnia According to OECD 202, Part 14. Existing study for Determination of the 72-hour EC 50 of “Brueggolit E02” towards Scenedesmus subspicatus (LAUS GmbH)5. Existing study for Algae Inhibition Test According to OECD 201 (Jaeger)0238Stripping and discharge agent for textiles, bleaching agent for molasses, soap.
1. Melting Point (ASTM E 324)2. Boiling Point (ASTM E1719), Water Partition Coefficient3. Water Solubility (ASTM E 1148) (40 CFR 799.6784)4. Genetic Toxicity (chromosomal damage) (40 CFR 799.6784)5. Combined Repeated Dose/Developmental/Reproductive Toxicity Test (40 CFR 799.9365)0309 
Heptenone, methyl- (CASRN 409-02-9)Physicochemical Properties, i.e., Melting Point, Boiling Point, Vapor Pressure, and n-Octanol/Water Partition Coefficient0324, transmittal; 0324.15Organic synthesis, inexpensive perfumes, flavoring.
Water Solubility0324 and 0324.13 
Ready Biodegradability: OECD 301F Manometric Respirometry Test0324 and 0324.12 
Fish Acute Toxicity Test0324 and 0324.11 
Daphnia sp., Acute Immobilization Test0324 and 0324.10 
Alga, Growth Inhibition Test0324 and 0324.9 
Acute Oral Toxicity to the Rat Test0324 and 0324.8 
Bacterial Reverse Mutation Test0324 and 0324.6 
In Vitro Mammalian Chromosome Aberration Test in Human Lymphocytes0324 and 0324.4 
Reproductive Developmental Toxicity Screening Test by Oral Gavage Administration to CD Rats0324, 0324.1, 0324.2 
Methane, isocyanato-(CASRN 624-83-9)Robust summaries of publicly available existing data on:1. Melting Point.2. Boiling Point.3. Vapor Pressure.4. Partition Coefficient.5. Solubility in Different Media: Solubility in Water.6. Stability in Water.7. Biodegradation.8. Acute/Prolonged Toxicity to Fish9. Acute Toxicity to Aquatic Invertebrates10. Toxicity to Aquatic Plants, e.g., Algae0249Production of pesticides, polyurethane foam, and plastics.
   
Benzenesulfonic acid, [[4-[[4-[(phenylamino)phenyl][4-(phenylimino)-2,5-cyclohexadien-1-ylidene]methyl]phenylamino]-(C.I. Pigment Blue 61) (CASRN 1324-76-1)These data were claimed as CBI. The public version includes a robust summary of existing data for:1. Acute Toxicity to Fish.2. Acute Mammalian toxicity.3. Ames Bacterial Reverse Mutation.4. Cytogenetic Micronucleous Assay (Chromosomal damage)0286 and 0322Intermediate for antifouling paint agents, catalyst in organic reactions, used by offset ink makers to produce inks for heatset, coldset and sheet-fed applications.
Existing data for:1. Melting Point.2. Boiling Point.3. Water Solubility.0185, 0246, and 0280 
These data were claimed as CBI. The public version includes a robust summary for n-Octanol/Water Partition Coefficient0185, 0246, 0318, and 0280 
These data were claimed as CBI. The public version includes a robust summary for Inherent Biodegradation0185, 0246, and 0279 
Data for Vapor Pressure0280 and 0318 
These data were submitted as CBI. The public version includes data on:1. Acute Toxicity in Daphnia Magna with C.I. Pigment Blue 612. Fresh Water Algae Growth Inhibition Test with C.I. Pigment Blue 613. Combined 28-Day Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test0318 
C.I. Solvent Black 7 (CASRN 8005-02-5)Existing data for: Inherent Biodegradation: ISO 9888 (Zahn-Wellens method)0168, transmittal; 0169, and 0184Plastics, rubber, Bakelite, ink, paint, carbon paper, and leather shoe coloring.
Acute Toxicity to Rainbow Trout by Zahn-Wellens test, OECD 302B0174 and 0184 
Acute Toxicity to Daphnia, Daphnia Static Acute, OECD 2020175 and 0184 
Acute Toxicity to Plants, Algae Growth Inhibition, OECD 2010176 and 0184 
Acute Mammalian Toxicity, Rat, OECD 4010170 and 0184 
Reverse Mutation Assay using Salmonella Typhimarium, OECD 4710171 and 0184 
Micronucleous Assay, Nigrossine Base Ex: Metaphase Analysis in Chi Cells In Vitro 0172 and 0184 
Twenty-Eight Day Sub-acute Oral (Gavage) Toxicity Study in the Rat, OECD 4070173 and 0184 
Determination of Physico-Chemical Properties of C.I. Solvent Black 7, including Melting Point ASTM E 324 (capillary tube)0290, transmittal; 0290.1, pg. 4; and 0290.2 
Boiling Point:ASTM E 1719 (ebulliometry)0290.1, pg. 7; and 0290.2 
Vapor Pressure: ASTM E 1782 (thermal analysis)0290.1, pg. 15; and 0290.2 
n-Octanol/Water Partition Coefficient0290, 0290.1, pg. 17; and 0290.2 
Water Solubility0290, 0290.1, pg. 20; and 0290.2 
A Prenatal Developmental Toxicity Study of C.I. Solvent Black 7 in Rats by Oral Gavage0290, 290.4, and 0184 
Urea, reaction products with formaldehyde (CASRN 68611-64-3)For Fulfillment of Data Requirements for Urea, Reaction Products with Formaldehyde under TSCA Section 40360 and 0361Adhesive or binder for particle board, medium density fiber board, hardwood plywood, glass fiber roofing materials.

Authority

15 U.S.C. 2603.

List of Subjects

Environmental protection, Hazardous substances.

Dated: June 21, 2011.
Maria J. Doa,
Director, Chemical Control Division, Office of Pollution Prevention and Toxics.
[FR Doc. 2011-16162 Filed 6-28-11; 8:45 am]
BILLING CODE 6560-50-P
 
 
Comments Not Accepted
ID: EPA-HQ-OPPT-2005-0033-0392
View original printed format:
PDF

Document Information

Date Posted: Jun 29, 2011
RIN: Not Assigned
Federal Register Number: 2011-16162
Show More Details  

Document text and images courtesy of the
Federal Register